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Peroxisome proliferator activated receptor-γ-Rho-kinase interactions contribute to vascular remodeling after chronic intrauterine pulmonary hypertension

Peroxisome proliferator-activated receptor-γ (PPARγ) and Rho-kinase (ROCK) regulate smooth muscle cell (SMC) proliferation and contribute to vascular remodeling in adult pulmonary hypertension. Whether these pathways interact to contribute to the development of vascular remodeling in persistent pulm...

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Detalhes bibliográficos
Main Authors: Gien, Jason, Tseng, Nancy, Seedorf, Gregory, Roe, Gates, Abman, Steven H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3920199/
https://ncbi.nlm.nih.gov/pubmed/24375792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00271.2013
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