Serotonin contributes to high pulmonary vascular tone in a sheep model of persistent pulmonary hypertension of the newborn

Although past studies demonstrate that altered serotonin (5-HT) signaling is present in adults with idiopathic pulmonary arterial hypertension, whether serotonin contributes to the pathogenesis of persistent pulmonary hypertension of the newborn (PPHN) is unknown. We hypothesized that 5-HT contribut...

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Autori principali: Delaney, Cassidy, Gien, Jason, Roe, Gates, Isenberg, Nicole, Kailey, Jenai, Abman, Steven H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3680750/
https://ncbi.nlm.nih.gov/pubmed/23605003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00043.2013
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