Serotonin 2A receptor inhibition protects against the development of pulmonary hypertension and pulmonary vascular remodeling in neonatal mice

Pulmonary hypertension (PH) complicating bronchopulmonary dysplasia (BPD) worsens clinical outcomes in former preterm infants. Increased serotonin (5-hydroxytryptamine, 5-HT) signaling plays a prominent role in PH pathogenesis and progression in adults. We hypothesized that increased 5-HT signaling...

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Bibliographic Details
Published in:Am J Physiol Lung Cell Mol Physiol
Main Authors: Delaney, Cassidy, Sherlock, Laurie, Fisher, Susan, Maltzahn, Joanne, Wright, Clyde, Nozik-Grayck, Eva
Format: Artigo
Language:Inglês
Published: American Physiological Society 2018
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6008134/
https://ncbi.nlm.nih.gov/pubmed/29345193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00215.2017
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