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Serotonin 2A receptor inhibition protects against the development of pulmonary hypertension and pulmonary vascular remodeling in neonatal mice

Pulmonary hypertension (PH) complicating bronchopulmonary dysplasia (BPD) worsens clinical outcomes in former preterm infants. Increased serotonin (5-hydroxytryptamine, 5-HT) signaling plays a prominent role in PH pathogenesis and progression in adults. We hypothesized that increased 5-HT signaling...

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Bibliografski detalji
Izdano u:Am J Physiol Lung Cell Mol Physiol
Glavni autori: Delaney, Cassidy, Sherlock, Laurie, Fisher, Susan, Maltzahn, Joanne, Wright, Clyde, Nozik-Grayck, Eva
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6008134/
https://ncbi.nlm.nih.gov/pubmed/29345193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00215.2017
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