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Redistribution of Extracellular Superoxide Dismutase Causes Neonatal Pulmonary Vascular Remodeling and PH but Protects Against Experimental Bronchopulmonary Dysplasia

Background: A naturally occurring single nucleotide polymorphism (SNP), (R(213)G), in extracellular superoxide dismutase (SOD3), decreases SOD3 matrix binding affinity. Humans and mature mice expressing the R(213)G SNP exhibit increased cardiovascular disease but decreased lung disease. The impact o...

詳細記述

保存先:
書誌詳細
出版年:Antioxidants (Basel)
主要な著者: Sherlock, Laurie G., Trumpie, Ashley, Hernandez-Lagunas, Laura, McKenna, Sarah, Fisher, Susan, Bowler, Russell, Wright, Clyde J., Delaney, Cassidy, Nozik-Grayck, Eva
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5874528/
https://ncbi.nlm.nih.gov/pubmed/29538340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox7030042
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