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Redistribution of Extracellular Superoxide Dismutase Causes Neonatal Pulmonary Vascular Remodeling and PH but Protects Against Experimental Bronchopulmonary Dysplasia

Background: A naturally occurring single nucleotide polymorphism (SNP), (R(213)G), in extracellular superoxide dismutase (SOD3), decreases SOD3 matrix binding affinity. Humans and mature mice expressing the R(213)G SNP exhibit increased cardiovascular disease but decreased lung disease. The impact o...

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Bibliografiske detaljer
Udgivet i:Antioxidants (Basel)
Main Authors: Sherlock, Laurie G., Trumpie, Ashley, Hernandez-Lagunas, Laura, McKenna, Sarah, Fisher, Susan, Bowler, Russell, Wright, Clyde J., Delaney, Cassidy, Nozik-Grayck, Eva
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5874528/
https://ncbi.nlm.nih.gov/pubmed/29538340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox7030042
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