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Serotonin 2A receptor inhibition protects against the development of pulmonary hypertension and pulmonary vascular remodeling in neonatal mice

Pulmonary hypertension (PH) complicating bronchopulmonary dysplasia (BPD) worsens clinical outcomes in former preterm infants. Increased serotonin (5-hydroxytryptamine, 5-HT) signaling plays a prominent role in PH pathogenesis and progression in adults. We hypothesized that increased 5-HT signaling...

詳細記述

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書誌詳細
出版年:Am J Physiol Lung Cell Mol Physiol
主要な著者: Delaney, Cassidy, Sherlock, Laurie, Fisher, Susan, Maltzahn, Joanne, Wright, Clyde, Nozik-Grayck, Eva
フォーマット: Artigo
言語:Inglês
出版事項: American Physiological Society 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6008134/
https://ncbi.nlm.nih.gov/pubmed/29345193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00215.2017
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