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Cinaciguat, a soluble guanylate cyclase activator, augments cGMP after oxidative stress and causes pulmonary vasodilation in neonatal pulmonary hypertension

Although inhaled NO (iNO) therapy is often effective in treating infants with persistent pulmonary hypertension of the newborn (PPHN), up to 40% of patients fail to respond, which may be partly due to abnormal expression and function of soluble guanylate cyclase (sGC). To determine whether altered s...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Chester, Marc, Seedorf, Gregory, Tourneux, Pierre, Gien, Jason, Tseng, Nancy, Grover, Theresa, Wright, Jason, Stasch, Johannes-Peter, Abman, Steven H.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Physiological Society 2011
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3213988/
https://ncbi.nlm.nih.gov/pubmed/21856817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00138.2010
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