Carregant...

Cinaciguat, a soluble guanylate cyclase activator, causes potent and sustained pulmonary vasodilation in the ovine fetus

Impaired nitric oxide-cGMP signaling contributes to severe pulmonary hypertension after birth, which may in part be due to decreased soluble guanylate cyclase (sGC) activity. Cinaciguat (BAY 58-2667) is a novel sGC activator that causes vasodilation, even in the presence of oxidized heme or heme-fre...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Chester, Marc, Tourneux, Pierre, Seedorf, Greg, Grover, Theresa R., Gien, Jason, Abman, Steven H.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2742799/
https://ncbi.nlm.nih.gov/pubmed/19465519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00062.2009
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!