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Bioactive Flavonoids and Catechols as Hif1 and Nrf2 Protein Stabilizers - Implications for Parkinson’s Disease

Flavonoids are known to trigger the intrinsic genetic adaptive programs to hypoxic or oxidative stress via estrogen receptor engagement or upstream kinase activation. To reveal specific structural requirements for direct stabilization of the transcription factors responsible for triggering the antih...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Aging Dis
Hauptverfasser: Smirnova, Natalya A., Kaidery, Navneet Ammal, Hushpulian, Dmitry M., Rakhman, Ilay I., Poloznikov, Andrey A., Tishkov, Vladimir I., Karuppagounder, Saravanan S., Gaisina, Irina N., Pekcec, Anton, Leyen, Klaus Van, Kazakov, Sergey V., Yang, Lichuan, Thomas, Bobby, Ratan, Rajiv R., Gazaryan, Irina G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: JKL International LLC 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5201116/
https://ncbi.nlm.nih.gov/pubmed/28053825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14336/AD.2016.0505
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