Bioactive Flavonoids and Catechols as Hif1 and Nrf2 Protein Stabilizers - Implications for Parkinson’s Disease

Flavonoids are known to trigger the intrinsic genetic adaptive programs to hypoxic or oxidative stress via estrogen receptor engagement or upstream kinase activation. To reveal specific structural requirements for direct stabilization of the transcription factors responsible for triggering the antih...

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Vydáno v:Aging Dis
Hlavní autoři: Smirnova, Natalya A., Kaidery, Navneet Ammal, Hushpulian, Dmitry M., Rakhman, Ilay I., Poloznikov, Andrey A., Tishkov, Vladimir I., Karuppagounder, Saravanan S., Gaisina, Irina N., Pekcec, Anton, Leyen, Klaus Van, Kazakov, Sergey V., Yang, Lichuan, Thomas, Bobby, Ratan, Rajiv R., Gazaryan, Irina G.
Médium: Artigo
Jazyk:Inglês
Vydáno: JKL International LLC 2016
Témata:
Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5201116/
https://ncbi.nlm.nih.gov/pubmed/28053825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14336/AD.2016.0505
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