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Bioactive Flavonoids and Catechols as Hif1 and Nrf2 Protein Stabilizers - Implications for Parkinson’s Disease

Flavonoids are known to trigger the intrinsic genetic adaptive programs to hypoxic or oxidative stress via estrogen receptor engagement or upstream kinase activation. To reveal specific structural requirements for direct stabilization of the transcription factors responsible for triggering the antih...

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Detalhes bibliográficos
Publicado no:Aging Dis
Main Authors: Smirnova, Natalya A., Kaidery, Navneet Ammal, Hushpulian, Dmitry M., Rakhman, Ilay I., Poloznikov, Andrey A., Tishkov, Vladimir I., Karuppagounder, Saravanan S., Gaisina, Irina N., Pekcec, Anton, Leyen, Klaus Van, Kazakov, Sergey V., Yang, Lichuan, Thomas, Bobby, Ratan, Rajiv R., Gazaryan, Irina G.
Formato: Artigo
Idioma:Inglês
Publicado em: JKL International LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5201116/
https://ncbi.nlm.nih.gov/pubmed/28053825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14336/AD.2016.0505
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