L-ascorbic acid: A true substrate for HIF prolyl hydroxylase?

L-Ascorbate (L-Asc), but not D-isoascorbate (D-Asc) and N-acetylcysteine (NAC) suppress HIF1 ODD-luc reporter activation induced by various inhibitors of HIF prolyl hydroxylase (PHD). The efficiency of suppression by L-Asc was sensitive to the nature of HIF PHD inhibitor chosen for reporter activati...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Biochimie
Huvudupphovsmän: Osipyants, Andrey I., Poloznikov, Andrey A., Smirnova, Natalya A., Hushpulian, Dmitry M., Khristichenko, Anna Yu., Chubar, Tatiana A., Zakhariants, Arpenik A., Ahuja, Manuj, Gaisina, Irina N., Thomas, Bobby, Brown, Abe M., Gazaryan, Irina G., Tishkov, Vladimir I.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2017
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6460286/
https://ncbi.nlm.nih.gov/pubmed/29289682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biochi.2017.12.011
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk