Targeting integrin α(5)β(1) ameliorates severe airway hyperresponsiveness in experimental asthma

Treatment options are limited for severe asthma, and the need for additional therapies remains great. Previously, we demonstrated that integrin α(v)β(6)-deficient mice are protected from airway hyperresponsiveness, due in part to increased expression of the murine ortholog of human chymase. Here, we...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:J Clin Invest
Main Authors: Sundaram, Aparna, Chen, Chun, Khalifeh-Soltani, Amin, Atakilit, Amha, Ren, Xin, Qiu, Wenli, Jo, Hyunil, DeGrado, William, Huang, Xiaozhu, Sheppard, Dean
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5199700/
https://ncbi.nlm.nih.gov/pubmed/27918306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI88555
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker