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Targeting integrin α(5)β(1) ameliorates severe airway hyperresponsiveness in experimental asthma
Treatment options are limited for severe asthma, and the need for additional therapies remains great. Previously, we demonstrated that integrin α(v)β(6)-deficient mice are protected from airway hyperresponsiveness, due in part to increased expression of the murine ortholog of human chymase. Here, we...
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| Publicado no: | J Clin Invest |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5199700/ https://ncbi.nlm.nih.gov/pubmed/27918306 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI88555 |
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