The αvβ6 integrin modulates airway hyperresponsiveness in mice by regulating intraepithelial mast cells

Allergic asthma is the most common form of asthma, affecting more than 10 million Americans. Although it is clear that mast cells have a key role in the pathogenesis of allergic asthma, the mechanisms by which they regulate airway narrowing in vivo remain to be elucidated. Here we report that mice l...

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Detalhes bibliográficos
Main Authors: Sugimoto, Kotaro, Kudo, Makoto, Sundaram, Aparna, Ren, Xin, Huang, Katherine, Bernstein, Xin, Wang, Yanli, Raymond, Wilfred W., Erle, David J., Åbrink, Magnus, Caughey, George H., Huang, Xiaozhu, Sheppard, Dean
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266785/
https://ncbi.nlm.nih.gov/pubmed/22232213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI58815
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