The phosphatase CD148 promotes airway hyperresponsiveness through SRC family kinases

Increased airway smooth muscle (ASM) contractility and the development of airway hyperresponsiveness (AHR) are cardinal features of asthma, but the signaling pathways that promote these changes are poorly understood. Tyrosine phosphorylation is tightly regulated by the opposing actions of protein ty...

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Bibliografski detalji
Glavni autori: Katsumoto, Tamiko R., Kudo, Makoto, Chen, Chun, Sundaram, Aparna, Callahan, Elliott C., Zhu, Jing W., Lin, Joseph, Rosen, Connor E., Manz, Boryana N., Lee, Jae W., Matthay, Michael A., Huang, Xiaozhu, Sheppard, Dean, Weiss, Arthur
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2013
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3635736/
https://ncbi.nlm.nih.gov/pubmed/23543053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI66397
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