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Structurally distinct phosphatases CD45 and CD148 both regulate B cell and macrophage immunoreceptor signaling

The receptor-type protein tyrosine phosphatase (RPTP) CD148 is thought to have an inhibitory function in signaling and proliferation in non-hematopoietic cells. However, its role in the immune system has not been thoroughly studied. Our analysis of CD148 loss of function mice suggests that CD148 has...

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Bibliographic Details
Main Authors: Zhu, Jing W., Brdicka, Tomas, Katsumoto, Tamiko R., Lin, Joseph, Weiss, Arthur
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265106/
https://ncbi.nlm.nih.gov/pubmed/18249142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2007.11.024
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