The αvβ6 integrin modulates airway hyperresponsiveness in mice by regulating intraepithelial mast cells

Allergic asthma is the most common form of asthma, affecting more than 10 million Americans. Although it is clear that mast cells have a key role in the pathogenesis of allergic asthma, the mechanisms by which they regulate airway narrowing in vivo remain to be elucidated. Here we report that mice l...

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Autors principals: Sugimoto, Kotaro, Kudo, Makoto, Sundaram, Aparna, Ren, Xin, Huang, Katherine, Bernstein, Xin, Wang, Yanli, Raymond, Wilfred W., Erle, David J., Åbrink, Magnus, Caughey, George H., Huang, Xiaozhu, Sheppard, Dean
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266785/
https://ncbi.nlm.nih.gov/pubmed/22232213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI58815
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