Mfge8 suppresses airway hyperresponsiveness in asthma by regulating smooth muscle contraction

Airway obstruction is a hallmark of allergic asthma and is caused primarily by airway smooth muscle (ASM) hypercontractility. Airway inflammation leads to the release of cytokines that enhance ASM contraction by increasing ras homolog gene family, member A (RhoA) activity. The protective mechanisms...

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Detaylı Bibliyografya
Asıl Yazarlar: Kudo, Makoto, Khalifeh Soltani, S. M. Amin, Sakuma, Stephen A., McKleroy, William, Lee, Ting-Hein, Woodruff, Prescott G., Lee, Jae Woo, Huang, Katherine, Chen, Chun, Arjomandi, Mehrdad, Huang, Xiaozhu, Atabai, Kamran
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2013
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545777/
https://ncbi.nlm.nih.gov/pubmed/23269839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1216673110
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