Mfge8 suppresses airway hyperresponsiveness in asthma by regulating smooth muscle contraction

Airway obstruction is a hallmark of allergic asthma and is caused primarily by airway smooth muscle (ASM) hypercontractility. Airway inflammation leads to the release of cytokines that enhance ASM contraction by increasing ras homolog gene family, member A (RhoA) activity. The protective mechanisms...

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Detalhes bibliográficos
Main Authors: Kudo, Makoto, Khalifeh Soltani, S. M. Amin, Sakuma, Stephen A., McKleroy, William, Lee, Ting-Hein, Woodruff, Prescott G., Lee, Jae Woo, Huang, Katherine, Chen, Chun, Arjomandi, Mehrdad, Huang, Xiaozhu, Atabai, Kamran
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545777/
https://ncbi.nlm.nih.gov/pubmed/23269839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1216673110
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