IQGAP1-dependent scaffold suppresses RhoA and inhibits airway smooth muscle contraction

The intracellular scaffold protein IQGAP1 supports protein complexes in conjunction with numerous binding partners involved in multiple cellular processes. Here, we determined that IQGAP1 modulates airway smooth muscle contractility. Compared with WT controls, at baseline as well as after immune sen...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Clin Invest
Päätekijät: Bhattacharya, Mallar, Sundaram, Aparna, Kudo, Makoto, Farmer, Jessica, Ganesan, Previn, Khalifeh-Soltani, Amin, Arjomandi, Mehrdad, Atabai, Kamran, Huang, Xiaozhu, Sheppard, Dean
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Clinical Investigation 2014
Aiheet:
Brief Report
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4347230/
https://ncbi.nlm.nih.gov/pubmed/25271629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI76658
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