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Functional genomic screen identifies novel mediators of collagen uptake
Tissue fibrosis occurs when matrix production outpaces matrix degradation. Degradation of collagen, the main component of fibrotic tissue, is mediated through an extracellular proteolytic pathway and intracellular pathway of cellular uptake and lysosomal digestion. Recent studies demonstrate that di...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Cell Biology
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3937085/ https://ncbi.nlm.nih.gov/pubmed/24403604 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E13-07-0382 |
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