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Mfge8 promotes obesity by mediating the uptake of dietary fats and serum fatty acids

Fatty acids are integral mediators of energy storage, membrane formation and cell signaling. The pathways that orchestrate uptake of fatty acids remain incompletely understood. Expression of the integrin ligand Mfge8 is increased in human obesity and in mice on a high-fat diet, but its role in obesi...

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Bibliographic Details
Published in:Nat Med
Main Authors: Khalifeh-Soltani, Amin, McKleroy, William, Sakuma, Stephen, Cheung, Yuk Yin, Tharp, Kevin, Qiu, Yifu, Turner, Scott M, Chawla, Ajay, Stahl, Andreas, Atabai, Kamran
Format: Artigo
Language:Inglês
Published: 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4273653/
https://ncbi.nlm.nih.gov/pubmed/24441829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3450
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