Mfge8 suppresses airway hyperresponsiveness in asthma by regulating smooth muscle contraction

Airway obstruction is a hallmark of allergic asthma and is caused primarily by airway smooth muscle (ASM) hypercontractility. Airway inflammation leads to the release of cytokines that enhance ASM contraction by increasing ras homolog gene family, member A (RhoA) activity. The protective mechanisms...

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Dades bibliogràfiques
Autors principals: Kudo, Makoto, Khalifeh Soltani, S. M. Amin, Sakuma, Stephen A., McKleroy, William, Lee, Ting-Hein, Woodruff, Prescott G., Lee, Jae Woo, Huang, Katherine, Chen, Chun, Arjomandi, Mehrdad, Huang, Xiaozhu, Atabai, Kamran
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2013
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545777/
https://ncbi.nlm.nih.gov/pubmed/23269839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1216673110
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