Mfge8 suppresses airway hyperresponsiveness in asthma by regulating smooth muscle contraction

Airway obstruction is a hallmark of allergic asthma and is caused primarily by airway smooth muscle (ASM) hypercontractility. Airway inflammation leads to the release of cytokines that enhance ASM contraction by increasing ras homolog gene family, member A (RhoA) activity. The protective mechanisms...

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Bibliografski detalji
Glavni autori: Kudo, Makoto, Khalifeh Soltani, S. M. Amin, Sakuma, Stephen A., McKleroy, William, Lee, Ting-Hein, Woodruff, Prescott G., Lee, Jae Woo, Huang, Katherine, Chen, Chun, Arjomandi, Mehrdad, Huang, Xiaozhu, Atabai, Kamran
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2013
Teme:
Biological Sciences
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545777/
https://ncbi.nlm.nih.gov/pubmed/23269839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1216673110
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