Mfge8 suppresses airway hyperresponsiveness in asthma by regulating smooth muscle contraction

Airway obstruction is a hallmark of allergic asthma and is caused primarily by airway smooth muscle (ASM) hypercontractility. Airway inflammation leads to the release of cytokines that enhance ASM contraction by increasing ras homolog gene family, member A (RhoA) activity. The protective mechanisms...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Kudo, Makoto, Khalifeh Soltani, S. M. Amin, Sakuma, Stephen A., McKleroy, William, Lee, Ting-Hein, Woodruff, Prescott G., Lee, Jae Woo, Huang, Katherine, Chen, Chun, Arjomandi, Mehrdad, Huang, Xiaozhu, Atabai, Kamran
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: National Academy of Sciences 2013
Θέματα:
Biological Sciences
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545777/
https://ncbi.nlm.nih.gov/pubmed/23269839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1216673110
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