Influence of Aluminium and EGCG on Fibrillation and Aggregation of Human Islet Amyloid Polypeptide

The abnormal fibrillation of human islet amyloid polypeptide (hIAPP) has been implicated in the development of type II diabetes. Aluminum is known to trigger the structural transformation of many amyloid proteins and induce the formation of toxic aggregate species. The (−)-epigallocatechin gallate (...

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Udgivet i:J Diabetes Res
Main Authors: Xu, Zhi-Xue, Zhang, Qiang, Ma, Gong-Li, Chen, Cong-Heng, He, Yan-Ming, Xu, Li-Hui, Zhang, Yuan, Zhou, Guang-Rong, Li, Zhen-Hua, Yang, Hong-Jie, Zhou, Ping
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5198260/
https://ncbi.nlm.nih.gov/pubmed/28074190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/1867059
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