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Influence of Aluminium and EGCG on Fibrillation and Aggregation of Human Islet Amyloid Polypeptide

The abnormal fibrillation of human islet amyloid polypeptide (hIAPP) has been implicated in the development of type II diabetes. Aluminum is known to trigger the structural transformation of many amyloid proteins and induce the formation of toxic aggregate species. The (−)-epigallocatechin gallate (...

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Detalhes bibliográficos
Publicado no:J Diabetes Res
Main Authors: Xu, Zhi-Xue, Zhang, Qiang, Ma, Gong-Li, Chen, Cong-Heng, He, Yan-Ming, Xu, Li-Hui, Zhang, Yuan, Zhou, Guang-Rong, Li, Zhen-Hua, Yang, Hong-Jie, Zhou, Ping
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5198260/
https://ncbi.nlm.nih.gov/pubmed/28074190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/1867059
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