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Influence of Aluminium and EGCG on Fibrillation and Aggregation of Human Islet Amyloid Polypeptide

The abnormal fibrillation of human islet amyloid polypeptide (hIAPP) has been implicated in the development of type II diabetes. Aluminum is known to trigger the structural transformation of many amyloid proteins and induce the formation of toxic aggregate species. The (−)-epigallocatechin gallate (...

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Bibliographische Detailangaben
Veröffentlicht in:J Diabetes Res
Hauptverfasser: Xu, Zhi-Xue, Zhang, Qiang, Ma, Gong-Li, Chen, Cong-Heng, He, Yan-Ming, Xu, Li-Hui, Zhang, Yuan, Zhou, Guang-Rong, Li, Zhen-Hua, Yang, Hong-Jie, Zhou, Ping
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5198260/
https://ncbi.nlm.nih.gov/pubmed/28074190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/1867059
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