Influence of Aluminium and EGCG on Fibrillation and Aggregation of Human Islet Amyloid Polypeptide

The abnormal fibrillation of human islet amyloid polypeptide (hIAPP) has been implicated in the development of type II diabetes. Aluminum is known to trigger the structural transformation of many amyloid proteins and induce the formation of toxic aggregate species. The (−)-epigallocatechin gallate (...

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Dettagli Bibliografici
Pubblicato in:J Diabetes Res
Autori principali: Xu, Zhi-Xue, Zhang, Qiang, Ma, Gong-Li, Chen, Cong-Heng, He, Yan-Ming, Xu, Li-Hui, Zhang, Yuan, Zhou, Guang-Rong, Li, Zhen-Hua, Yang, Hong-Jie, Zhou, Ping
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi Publishing Corporation 2016
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5198260/
https://ncbi.nlm.nih.gov/pubmed/28074190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/1867059
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