Identification of an alternative ligand-binding pocket in the nuclear vitamin D receptor and its functional importance in 1α,25(OH)(2)-vitamin D(3) signaling

Podobné jednotky

• New Insights into Vitamin D Sterol-VDR Proteolysis, Allostery, Structure-Function from the Perspective of a Conformational Ensemble Model
  Autor: Mizwicki, Mathew T., a další
  Vydáno: (2007)
• Conservative Mutageneic Perturbations of Amino Acids Connecting Helix 12 in the 1α,25(OH)(2)-D(3) Receptor (VDR) to the Ligand Cause Significant Transactivational Effects
  Autor: Bula, Craig M., a další
  Vydáno: (2007)
• Vitamin D Receptor (VDR) Regulation of Voltage-Gated Chloride Channels by Ligands Preferring a VDR-Alternative Pocket (VDR-AP)
  Autor: Menegaz, Danusa, a další
  Vydáno: (2011)
• On the Mechanism Underlying (23S)-25-Dehydro-1α(OH)-vitamin D(3)-26,23-lactone Antagonism of hVDRwt Gene Activation and Its Switch to a Superagonist
  Autor: Mizwicki, Mathew T., a další
  Vydáno: (2009)
• A molecular description of ligand binding to the two overlapping binding pockets of the nuclear vitamin D receptor (VDR): structure-function implications
  Autor: Mizwicki, Mathew T., a další
  Vydáno: (2010)