Vitamin D Receptor (VDR) Regulation of Voltage-Gated Chloride Channels by Ligands Preferring a VDR-Alternative Pocket (VDR-AP)

We have postulated that the vitamin D receptor (VDR) contains two overlapping ligand binding sites, a genomic pocket and an alternative pocket (AP), that mediate regulation of gene transcription and rapid responses, respectively. Flexible VDR + ligand docking calculations predict that the major bloo...

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Hlavní autoři: Menegaz, Danusa, Mizwicki, Mathew T., Barrientos-Duran, Antonio, Chen, Ning, Henry, Helen L., Norman, Anthony W.
Médium: Artigo
Jazyk:Inglês
Vydáno: Endocrine Society 2011
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3146250/
https://ncbi.nlm.nih.gov/pubmed/21659475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2010-0442
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