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Identification of an alternative ligand-binding pocket in the nuclear vitamin D receptor and its functional importance in 1α,25(OH)(2)-vitamin D(3) signaling
Structural and molecular studies have shown that the vitamin D receptor (VDR) mediates 1α,25(OH)(2)-vitamin D(3) gene transactivation. Recent evidence indicates that both VDR and the estrogen receptor are localized to plasma membrane caveolae and are required for initiation of nongenomic (NG) respon...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC516488/ https://ncbi.nlm.nih.gov/pubmed/15326291 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0403606101 |
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