Membrane-Bound Alpha Synuclein Clusters Induce Impaired Lipid Diffusion and Increased Lipid Packing

The aggregation of membrane-bound α-synuclein (αS) into oligomers and/or amyloid fibrils has been suggested to cause membrane damage in in vitro model phospholipid membrane systems and in vivo. In this study, we investigate how αS interactions that precede the formation of well-defined aggregates in...

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Detaylı Bibliyografya
Yayımlandı:Biophys J
Asıl Yazarlar: Iyer, Aditya, Schilderink, Nathalie, Claessens, Mireille M.A. E., Subramaniam, Vinod
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Biophysical Society 2016
Konular:
Membranes
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5153541/
https://ncbi.nlm.nih.gov/pubmed/27926845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.10.016
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