Membrane-Bound Alpha Synuclein Clusters Induce Impaired Lipid Diffusion and Increased Lipid Packing

The aggregation of membrane-bound α-synuclein (αS) into oligomers and/or amyloid fibrils has been suggested to cause membrane damage in in vitro model phospholipid membrane systems and in vivo. In this study, we investigate how αS interactions that precede the formation of well-defined aggregates in...

Full description

Saved in:
Bibliographic Details
Published in:Biophys J
Main Authors: Iyer, Aditya, Schilderink, Nathalie, Claessens, Mireille M.A. E., Subramaniam, Vinod
Format: Artigo
Language:Inglês
Published: The Biophysical Society 2016
Subjects:
Membranes
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5153541/
https://ncbi.nlm.nih.gov/pubmed/27926845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.10.016
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items