Membrane-Bound Alpha Synuclein Clusters Induce Impaired Lipid Diffusion and Increased Lipid Packing

The aggregation of membrane-bound α-synuclein (αS) into oligomers and/or amyloid fibrils has been suggested to cause membrane damage in in vitro model phospholipid membrane systems and in vivo. In this study, we investigate how αS interactions that precede the formation of well-defined aggregates in...

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Vydáno v:Biophys J
Hlavní autoři: Iyer, Aditya, Schilderink, Nathalie, Claessens, Mireille M.A. E., Subramaniam, Vinod
Médium: Artigo
Jazyk:Inglês
Vydáno: The Biophysical Society 2016
Témata:
Membranes
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5153541/
https://ncbi.nlm.nih.gov/pubmed/27926845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.10.016
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