C-Terminal Truncated α-Synuclein Fibrils Contain Strongly Twisted β-Sheets

[Image: see text] C-terminal truncations of monomeric wild-type alpha-synuclein (henceforth WT-αS) have been shown to enhance the formation of amyloid aggregates both in vivo and in vitro and have been associated with accelerated progression of Parkinson’s disease (PD). The correlation with PD may n...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:J Am Chem Soc
Auteurs principaux: Iyer, Aditya, Roeters, Steven J., Kogan, Vladimir, Woutersen, Sander, Claessens, Mireille M. A. E, Subramaniam, Vinod
Format: Artigo
Langue:Inglês
Publié: American Chemical Society 2017
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5668890/
https://ncbi.nlm.nih.gov/pubmed/28968082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b07403
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires