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Direct Visualization of Model Membrane Remodeling by α‐Synuclein Fibrillization

The interaction of α‐synuclein (αS) with membranes is thought to be critical in the etiology of Parkinson's disease. Besides oligomeric αS aggregates that possibly form membrane pores, the aggregation of αS into amyloid fibrils has been reported to disrupt membranes. The mechanism by which aggr...

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Publicat a:Chemphyschem
Autors principals: Chaudhary, Himanshu, Subramaniam, Vinod, Claessens, Mireille M. A. E.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5485007/
https://ncbi.nlm.nih.gov/pubmed/28370874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cphc.201700050
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