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Elucidating the Aggregation Number of Dopamine-Induced α-Synuclein Oligomeric Assemblies

Conventional methods to determine the aggregation number, that is, the number of monomers per oligomer, struggle to yield reliable results for large protein aggregates, such as amyloid oligomers. We have previously demonstrated the use of a combination of single-molecule photobleaching and substoich...

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Autori principali: Zijlstra, Niels, Claessens, Mireille M.A.E., Blum, Christian, Subramaniam, Vinod
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Biophysical Society 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3907248/
https://ncbi.nlm.nih.gov/pubmed/24461019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.12.009
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