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Elucidating the Aggregation Number of Dopamine-Induced α-Synuclein Oligomeric Assemblies

Conventional methods to determine the aggregation number, that is, the number of monomers per oligomer, struggle to yield reliable results for large protein aggregates, such as amyloid oligomers. We have previously demonstrated the use of a combination of single-molecule photobleaching and substoich...

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Detalhes bibliográficos
Main Authors: Zijlstra, Niels, Claessens, Mireille M.A.E., Blum, Christian, Subramaniam, Vinod
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3907248/
https://ncbi.nlm.nih.gov/pubmed/24461019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.12.009
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