Elucidating the Aggregation Number of Dopamine-Induced α-Synuclein Oligomeric Assemblies

Conventional methods to determine the aggregation number, that is, the number of monomers per oligomer, struggle to yield reliable results for large protein aggregates, such as amyloid oligomers. We have previously demonstrated the use of a combination of single-molecule photobleaching and substoich...

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Библиографические подробности
Главные авторы: Zijlstra, Niels, Claessens, Mireille M.A.E., Blum, Christian, Subramaniam, Vinod
Формат: Artigo
Язык:Inglês
Опубликовано: The Biophysical Society 2014
Предметы:
Proteins and Nucleic Acids
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3907248/
https://ncbi.nlm.nih.gov/pubmed/24461019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.12.009
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