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Elucidating the Aggregation Number of Dopamine-Induced α-Synuclein Oligomeric Assemblies

Conventional methods to determine the aggregation number, that is, the number of monomers per oligomer, struggle to yield reliable results for large protein aggregates, such as amyloid oligomers. We have previously demonstrated the use of a combination of single-molecule photobleaching and substoich...

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Bibliografiska uppgifter
Huvudupphovsmän: Zijlstra, Niels, Claessens, Mireille M.A.E., Blum, Christian, Subramaniam, Vinod
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Biophysical Society 2014
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3907248/
https://ncbi.nlm.nih.gov/pubmed/24461019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.12.009
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