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Direct Visualization of Model Membrane Remodeling by α‐Synuclein Fibrillization

The interaction of α‐synuclein (αS) with membranes is thought to be critical in the etiology of Parkinson's disease. Besides oligomeric αS aggregates that possibly form membrane pores, the aggregation of αS into amyloid fibrils has been reported to disrupt membranes. The mechanism by which aggr...

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Bibliographic Details
Published in:Chemphyschem
Main Authors: Chaudhary, Himanshu, Subramaniam, Vinod, Claessens, Mireille M. A. E.
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5485007/
https://ncbi.nlm.nih.gov/pubmed/28370874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cphc.201700050
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