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Modeling Axonal Defects in Hereditary Spastic Paraplegia with Human Pluripotent Stem Cells
BACKGROUND: Cortical motor neurons, also known as upper motor neurons, are large projection neurons whose axons convey signals to lower motor neurons to control the muscle movements. Degeneration of cortical motor neuron axons is implicated in several debilitating disorders, including hereditary spa...
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| Publicado en: | Front Biol (Beijing) |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5147749/ https://ncbi.nlm.nih.gov/pubmed/27956894 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11515-016-1416-0 |
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