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Pharmacologic rescue of axon growth defects in a human iPSC model of hereditary spastic paraplegia SPG3A
Hereditary spastic paraplegias are a large, diverse group of neurological disorders (SPG1-71) with the unifying feature of prominent lower extremity spasticity, owing to a length-dependent axonopathy of corticospinal motor neurons. The most common early-onset form of pure, autosomal dominant heredit...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4189900/ https://ncbi.nlm.nih.gov/pubmed/24908668 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddu280 |
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