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Pharmacologic rescue of axon growth defects in a human iPSC model of hereditary spastic paraplegia SPG3A

Hereditary spastic paraplegias are a large, diverse group of neurological disorders (SPG1-71) with the unifying feature of prominent lower extremity spasticity, owing to a length-dependent axonopathy of corticospinal motor neurons. The most common early-onset form of pure, autosomal dominant heredit...

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Detaylı Bibliyografya
Asıl Yazarlar: Zhu, Peng-Peng, Denton, Kyle R., Pierson, Tyler Mark, Li, Xue-Jun, Blackstone, Craig
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4189900/
https://ncbi.nlm.nih.gov/pubmed/24908668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddu280
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