Rescue axonal defects by targeting mitochondrial dynamics in hereditary spastic paraplegias

Impaired axonal development and degeneration underlie debilitating neurodegenerative diseases including hereditary spastic paraplegia, a large group of inherited diseases. Hereditary spastic paraplegia is caused by retrograde degeneration of the long corticospinal tract axons, leading to progressive...

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Detaylı Bibliyografya
Asıl Yazarlar: Yongchao Mou, Xue-Jun Li
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Wolters Kluwer Medknow Publications 2019-01-01
Seri Bilgileri:Neural Regeneration Research
Konular:
hereditary spastic paraplegia; axonal degeneration; mitochondrial dynamics; fission; fusion; dynamin-related protein 1; mitochondrial dysfunction; induced pluripotent stem cells
Online Erişim:http://www.nrronline.org/article.asp?issn=1673-5374;year=2019;volume=14;issue=4;spage=574;epage=577;aulast=Mou
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