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Modeling Axonal Defects in Hereditary Spastic Paraplegia with Human Pluripotent Stem Cells
BACKGROUND: Cortical motor neurons, also known as upper motor neurons, are large projection neurons whose axons convey signals to lower motor neurons to control the muscle movements. Degeneration of cortical motor neuron axons is implicated in several debilitating disorders, including hereditary spa...
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| Publié dans: | Front Biol (Beijing) |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5147749/ https://ncbi.nlm.nih.gov/pubmed/27956894 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11515-016-1416-0 |
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