SNP rs16906252C>T is an expression and methylation quantitative trait locus associated with an increased risk of developing MGMT-methylated colorectal cancer

PURPOSE: Methylation of the MGMT promoter is the major cause of O(6)-methylguanine methyltransferase deficiency in cancer and has been associated with the T variant of the promoter-enhancer SNP rs16906252C>T. We sought evidence for an association between the rs16906252C>T genotype and increase...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Kuroiwa-Trzmielina, Joice, Wang, Fan, Rapkins, Robert W., Ward, Robyn L., Buchanan, Daniel D., Win, Aung Ko, Clendenning, Mark, Rosty, Christophe, Southey, Melissa C., Winship, Ingrid M., Hopper, John L., Jenkins, Mark A., Olivier, Jake, Hawkins, Nicholas J., Hitchins, Megan P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5143212/
https://ncbi.nlm.nih.gov/pubmed/27267851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-2765
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados