Genetic variants within the hTERT gene and the risk of colorectal cancer in Lynch syndrome

Lynch syndrome is an inherited cancer-predisposing disorder caused by germline mutations in the DNA mismatch repair (MMR) genes but there is a high degree of variability in cancer risk observed among carriers, suggesting the existence of modifying factors. Our aim was to investigate variants within...

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Detalhes bibliográficos
Publicado no:Genes Cancer
Main Authors: Win, Aung Ko, Clendenning, Mark, Crawford, William, Rosty, Christophe, Preston, Susan G., Southey, Melissa C., Parry, Susan, Giles, Graham G., Macrae, Finlay A., Winship, Ingrid M., Baron, John A., Hopper, John L., Jenkins, Mark A., Buchanan, Daniel D.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4701223/
https://ncbi.nlm.nih.gov/pubmed/26807197
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