Genetic variants within the hTERT gene and the risk of colorectal cancer in Lynch syndrome

Lynch syndrome is an inherited cancer-predisposing disorder caused by germline mutations in the DNA mismatch repair (MMR) genes but there is a high degree of variability in cancer risk observed among carriers, suggesting the existence of modifying factors. Our aim was to investigate variants within...

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Bibliografiska uppgifter
I publikationen:Genes Cancer
Huvudupphovsmän: Win, Aung Ko, Clendenning, Mark, Crawford, William, Rosty, Christophe, Preston, Susan G., Southey, Melissa C., Parry, Susan, Giles, Graham G., Macrae, Finlay A., Winship, Ingrid M., Baron, John A., Hopper, John L., Jenkins, Mark A., Buchanan, Daniel D.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Impact Journals LLC 2015
Ämnen:
Review
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4701223/
https://ncbi.nlm.nih.gov/pubmed/26807197
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