Antimalarial Activity of KAF156 in Falciparum and Vivax Malaria

BACKGROUND: KAF156 belongs to a new class of antimalarial agents (imidazolopiperazines), with activity against asexual and sexual blood stages and the preerythrocytic liver stages of malarial parasites. METHODS: We conducted a phase 2, open-label, two-part study at five centers in Thailand and Vietn...

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Dades bibliogràfiques
Publicat a:N Engl J Med
Autors principals: White, Nicholas J., Duong, Tran T., Uthaisin, Chirapong, Nosten, François, Phyo, Aung P., Hanboonkunupakarn, Borimas, Pukrittayakamee, Sasithon, Jittamala, Podjanee, Chuthasmit, Kittiphum, Cheung, Ming S., Feng, Yiyan, Li, Ruobing, Magnusson, Baldur, Sultan, Marc, Wieser, Daniela, Xun, Xiaolei, Zhao, Rong, Diagana, Thierry T., Pertel, Peter, Leong, F. Joel
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5142602/
https://ncbi.nlm.nih.gov/pubmed/27653565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1602250
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