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Spiroindolone KAE609 for Falciparum and Vivax Malaria
BACKGROUND: KAE609 (cipargamin; formerly NITD609, Novartis Institute for Tropical Diseases) is a new synthetic antimalarial spiroindolone analogue with potent, dose-dependent antimalarial activity against asexual and sexual stages of Plasmodium falciparum. METHODS: We conducted a phase 2, open-label...
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| Main Authors: | , , , , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2014
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4143746/ https://ncbi.nlm.nih.gov/pubmed/25075833 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1315860 |
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