Spiroindolone KAE609 for Falciparum and Vivax Malaria

BACKGROUND: KAE609 (cipargamin; formerly NITD609, Novartis Institute for Tropical Diseases) is a new synthetic antimalarial spiroindolone analogue with potent, dose-dependent antimalarial activity against asexual and sexual stages of Plasmodium falciparum. METHODS: We conducted a phase 2, open-label...

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Main Authors: White, Nicholas J., Pukrittayakamee, Sasithon, Phyo, Aung Pyae, Rueangweerayut, Ronnatrai, Nosten, François, Jittamala, Podjanee, Jeeyapant, Atthanee, Jain, Jay Prakash, Lefèvre, Gilbert, Li, Ruobing, Magnusson, Baldur, Diagana, Thierry T., Leong, F. Joel
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4143746/
https://ncbi.nlm.nih.gov/pubmed/25075833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1315860
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