Antimalarial Activity of KAF156 in Falciparum and Vivax Malaria

BACKGROUND: KAF156 belongs to a new class of antimalarial agents (imidazolopiperazines), with activity against asexual and sexual blood stages and the preerythrocytic liver stages of malarial parasites. METHODS: We conducted a phase 2, open-label, two-part study at five centers in Thailand and Vietn...

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Bibliografske podrobnosti
izdano v:N Engl J Med
Main Authors: White, Nicholas J., Duong, Tran T., Uthaisin, Chirapong, Nosten, François, Phyo, Aung P., Hanboonkunupakarn, Borimas, Pukrittayakamee, Sasithon, Jittamala, Podjanee, Chuthasmit, Kittiphum, Cheung, Ming S., Feng, Yiyan, Li, Ruobing, Magnusson, Baldur, Sultan, Marc, Wieser, Daniela, Xun, Xiaolei, Zhao, Rong, Diagana, Thierry T., Pertel, Peter, Leong, F. Joel
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5142602/
https://ncbi.nlm.nih.gov/pubmed/27653565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1602250
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