Enantiospecific pharmacokinetics and drug–drug interactions of primaquine and blood-stage antimalarial drugs

OBJECTIVES: Characterization of the pharmacokinetic properties of the enantiomers of primaquine and carboxyprimaquine following administration of racemic primaquine given alone and in combination with commonly used antimalarial drugs. METHODS: Enantiomeric pharmacokinetics were evaluated in 49 healt...

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Bibliografski detalji
Izdano u:J Antimicrob Chemother
Glavni autori: Chairat, Kalayanee, Jittamala, Podjanee, Hanboonkunupakarn, Borimas, Pukrittayakamee, Sasithon, Hanpithakpong, Warunee, Blessborn, Daniel, White, Nicholas J, Day, Nicholas P J, Tarning, Joel
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2018
Teme:
Original Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6198747/
https://ncbi.nlm.nih.gov/pubmed/30085149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dky297
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