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Population pharmacokinetics and electrocardiographic effects of dihydroartemisinin–piperaquine in healthy volunteers

AIMS: The aims of the present study were to evaluate the pharmacokinetic properties of dihydroartemisinin (DHA) and piperaquine, potential drug–drug interactions with concomitant primaquine treatment, and piperaquine effects on the electrocardiogram in healthy volunteers. METHODS: The population pha...

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Bibliografiska uppgifter
I publikationen:Br J Clin Pharmacol
Huvudupphovsmän: Chotsiri, Palang, Wattanakul, Thanaporn, Hoglund, Richard M., Hanboonkunupakarn, Borimas, Pukrittayakamee, Sasithon, Blessborn, Daniel, Jittamala, Podjanee, White, Nicholas J., Day, Nicholas P.J., Tarning, Joel
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5698590/
https://ncbi.nlm.nih.gov/pubmed/28695570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13372
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